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Iga Swiatek vs. Karolina Muchova

Count Swiatek as a Muchova stan.

“Honestly, I love playing against her,” the Pole says of the Czech. “I also love watching Karolina. It’s just nice to see someone who plays so smart and so smooth. She’s like woman’s Roger [Federer]."

“Woman’s Roger” has been living up to that lofty nickname of late. Muchova is coming off a title run at the 1000 in Doha last month, and is riding an eight-match win streak. But as much as Iga loves her game, she also knows how to counter it. Swiatek is 4-1 against Muchova, and hasn’t lost to her since 2019. When they played in this round at Indian Wells a year ago, she won 6-1, 6-1.

Read More: Iga Swiatek begins her milestone 250th career week in the Top 10 of the WTA rankings

Just don’t tell Swiatek it’s going to be that easy on Wednesday.

“The head-to-head might be to my side, but I can remember all these matches I played against her, sometimes I was down, like, break in third,” Swiatek says. “She’s an amazing player, and most of the times we played really tight matches.”

One of them happened in the 2023 Roland Garros final, which Swiatek won 6-4 in the third.

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This feels like it could be just as close. When Muchova has everything clicking, as she does now, she’s a Top 5 talent with the capability of beating anyone on any surface. The medium-slow courts in Indian Wells would seem to be her liking, and give her chances to do what she loves best: Send a ground stroke into a corner and close the net behind it. That’s how she has had success against Iga in the past.

So far this year, Swiatek hasn’t been as sharp as Muchova. But she seems motivated by that fact. After losing to Maria Sakkari in Doha, she skipped Dubai, went to work on her footwork and preparation, and got revenge on Sakkari, 6-3, 6-2 on Monday.

Still, this seems like a chance to pick Muchova to get a win over Swiatek, so I’ll take it. Winner: Muchova

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Carlos Alcaraz vs. Casper Ruud

Will Ruud raise his game to Maestro-like levels on Wednesday? Alcaraz is probably betting on it.

“I just sometimes get tired of\] [playing Roger Federer every round,” Alcaraz said after coming from a set down to beat Arthur Rinderknech on Monday. “Sometimes just feel like, yeah, they're playing really an insane level.”

This is a downside of being No. 1: Nobody feels like they have anything to lose against you, at least when they walk on the court, so they’re loose and relaxed—and often at their best. Serena Williams got tired of it, and now Alcaraz has, too.

“All can I do is just accept it, keep going, trying to, like, do different things in the match,” he said.

Read More: Why Carlos Alcaraz is tired of playing "Roger Federer" during latest winning streak

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Is Ruud the next man to turn into Roger against Carlitos? Ruud’s typical level is better than Rinderknech’s, so a competitive match wouldn’t come as a surprise to the Spaniard. He beat Alcaraz on an indoor hard court in 2024, and pushed him to 6-4 in the third on an outdoor hard court in Tokyo last fall. He has also been ranked as high as No. 2 in the world. If Ruud starts zoning, it may not be quite as irritating to Alcaraz.

Ruud’s 2026 hasn’t been much to write home about, but he did grit his way through a three-setter in his last match, vs. Valentin Vacherot. He has been to the quarters in Indian Wells, and the courts should suit him again. Ruud also has a forehand that is at least in the same ballpark as Alcaraz’s, something very few other humans can say.

Maybe most important, Rinderknech showed that Alcaraz isn’t just going to mow down everyone he faces in 2026. But that doesn’t mean he’s ready to lose just yet, either. Win streaks are good for motivation. Winner: Alcaraz

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Novak Djokovic vs. Jack Draper

Draper is the defending champion, and Djokovic is Djokovic. But it’s still a little bit of a surprise to see them in the round of 16 here. The Brit only returned to the tour in February, after eight months off due to a bone bruise to his left arm. The Serb, meanwhile, hasn’t made it this far in Indian Wells since 2017. But here they are, in what feels like a bonus marquee matchup.

It’s also a matchup we haven’t seen enough of. They haven’t played since 2021, when Djokovic sent a very young Draper packing in the first round at Wimbledon. Still, Draper showed something that day, winning a set before Djokovic settled in and ran away with the last three.

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Djokovic seemed a little uncertain about making the trip to Indian Wells; he didn’t commit until the last minute. Despite his performance at the Australian Open in January, he might have feared that another early exit in the desert was in the cards. And it almost was: Each of his first two matches has gone the distance. Now that he’s established himself at the event again, maybe his investment in it will increase; he is a five-time champ at Indian Wells, after all.

Just as important, his opponent may not be ready to fully invest, or believe, just yet.

“I’m going to have to play really well and take my chances,” Draper says of facing Djokovic. “But more than anything, just very grateful to not only be out here but to be having the opportunity to play against these guys.”

I’m not sure that sounds like someone who thinks he’s ready to beat Novak Djokovic. Winner: Djokovic